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IL-4 mRNA was found almost exclusively in the allergic patients. Osteoblast-derived factors also increased the formation of long protrusions and loss of cell-cell contacts in PC-3U cells, suggesting induction of a more aggressive phenotype. Taken together, the main result of this thesis is that neurotrophic factors indeed can work as autocrine survival factors in the developing CNS. We defined precision as 2. The median naevus count and prevalence of dysplastic naevi were significantly lower than previously described in populations with higher melanoma incidence and higher ambient ultraviolet exposure in southern Sweden. Presence of inflammation at the time of TURP did not differ between cases and controls nor were there differences in p53 or AR staining.

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Uppsala universitet, Medicinska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap.

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The naevus phenotype in a population in northern Sweden paper II The naevus phenotype was investigated in a population living in the inland of northern Sweden with a low melanoma incidence. Primary end points were a visible intracoronary thrombus and total vessel occlusion prior to percutaneous coronary intervention. Superficial spreading melanoma was the most frequent subtype, followed by nodular melanoma. During SSC, the conduction of heat from parent to infant is sufficiently high to compensate for the increase in evaporative and convective heat loss. In younger children the incidence remained extremely low, only 4 cases in children aged 0—9 years were reported during the studied year period. The aim of this observational study was to biochemically characterize the anaemia in GCA giant cell arteritis and PMR polymyalgia rheumatica patients.

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